Emphasizing the interconnectedness of human, animal, and environmental health, this session promotes the One Health approach to understanding and addressing infectious diseases. Discussions will explore the role of wildlife reservoirs, environmental factors, and socio-economic drivers in disease transmission. Collaborative efforts across disciplines are essential for early detection, prevention, and control of zoonotic diseases and other health threats at the human-animal-environment interface. By advocating for a holistic approach to infectious disease management, this session aims to foster interdisciplinary collaboration, improve health outcomes, and mitigate global health risks.