PharmaTech 2025: The Future of Pharmaceutics and Drug Innovations

Shuaib Alahmad Profile

Shuaib Alahmad

Shuaib Alahmad

Biography

A Syrian researcher who has worked on numerous important studies. Bachelor's degree in Pharmacy and Pharmaceutical Chemistry Master's degree in Drug Control PhD in Pharmaceutical Analytical Chemistry Dean of the Faculty of Pharmacy at the Al Watanyia Private University - Hama, Syria, 2021 to date Lecturer at the Al Watanyia Private University - Hama, Syria, 2020 to date Lecturer at the International University for Science and Technology - Damascus, Syria, 2019-2020 Lecturer at Al-Safwa University College - Karbala, Iraq, 2018-2019 Lecturer at the National University for Science and Technology - Dhi Qar, Iraq, 2018 Assistant lecturer at Tanta University - Egypt, 2015-2018 Assistant lecturer at Al-Qalamoun Private University, 2014 Member of the Scientific Council of the Syrian Board in Drug Control Reviewer of numerous international journals

Research Interest

The Faculty of Pharmacy at Al- Wataniya Private University also supports scientific research, as it is equipped with the latest laboratories and scientific research equipment. It has provided all research tools and modern scientific equipment and kept pace with everything new in applied scientific research, which contributed to increasing the number of internationally published research and obtaining an advanced ranking in the national classification.

Abstract

Chemometric Methods for Simultaneous Determination of Thioctic Acid, Benfotiamine and Cyanocobalamin in Their Dosage Form

Chemometric spectrophotometric methods for the simultaneous determination of thioctic acid (TCA), benfotiamine (BEN) and cyanocobalamin (CYN) in their dosage form were developed. These methods are based on chemometric treatment of data, the applied chemometric techniques are multivariate methods including partial least squares (PLS) and principal component regression (PCR). In these techniques, the concentration data matrix were prepared by using the synthetic mixtures containing the three drugs dissolved in water. The UV spectra were recorded within the wavelength range 278-298 nm at 1 nm intervals, the results were used to construct the multivariate calibrations as PLS, PCR. The spectrophotometric procedures do not require any separation step. The accuracy , precision and the linearity ranges of the methods have been determined and validated by analyzing synthetic mixtures containing the studied drugs. The developed methods were successfully applied to the synthetic mixtures and the results were compared to those obtained by a reported HPLC method.