Rosa Lelyana
Biography
Dr. Rr Haj Rosa Lelyana, PhD is a medical doctor, nutrition scientist, and senior lecturer at the Faculty of Medicine, Diponegoro University, Semarang, Indonesia. She holds an MD, a Master's in Biomedical Nutrition, and a PhD in Nutrition (Selinus University, Italy). Her research focuses on coffee's health effects, obesity, uric acid, and nutritional medicine.
She has authored numerous international journal articles, reviewed over 300 manuscripts, and served on editorial boards of more than 21 journals. Dr. Lelyana has been invited as a keynote speaker at international conferences, received multiple awards including Best Researcher International Award and Outstanding Researcher Award, and holds patents related to coffee-based health innovations.
Research Interest
Founder/Inventor in 1995y for the research : Personality Characters Will Impact Stress Response in Semester 6 of MD/Medical Doctor Students of Medicine Faculty of Diponegoro University, Indonesia; Master Programme (Thesis) for Coffee and Uric Acid Research graduation from Medicine Faculty of Diponegoro University in 2008
Abstract
Coffee As Antidepressant:
Depression is a serious and complex mood disorder which characteristic by feeling long sadness like loneliness.
Coffee is a favorite drink in this world. Many people love for drinking coffee but lack of understanding that drinking coffee will reduce the risk of depression.
So, this review study will discuss the bioechanism of coffee that have anti depressant activity.
Methode: Review study.
Results and Discussion:
Coffee contain caffeic acid. Caffeic acid is a phenolic acid compound which induce antidepressant like and neuroprotective effects. Caffeine is one of psychoactive substances which has activity to block the adenosine reseptor subunit. Caffeine in the coffee is an antagonists of adenosine reseptors which may enhance antidepressant effect in the low dose of caffeine and will produce rapid antideppresant action by reduction the depressive level. Low dose of caffeine will improve the cognitive performance in depressed patients. Chronic caffeine consumption will normalize salivary cortisol.
