Dr. Rosa Lelyana is a distinguished medical doctor, scientist, and educator specializing in nutrition, with a particular focus on coffee research. She holds an MD from Diponegoro University, Indonesia, and a PhD in Nutrition from Selinus University, Italy. Dr. Rosa is a senior lecturer at the Faculty of Medicine, Diponegoro University, and the creator of Gizi Estetik, a health and nutrition consultancy. She is an accomplished researcher, editor, and reviewer for numerous international journals, with expertise in the health benefits of coffee, nutrition, and medicine.
Educational Background
Key Research Contributions
Professional Experience
Awards and Achievements
Memberships
Coffee
Obesity,Adipose Tissue and Fat Abdominal
Uric Acid/Hyperuricemia
Medicine,,Health, Nutrition
Drug and Herbal Medicine
Diet & Thermogenesis (Diet & Molecular Nutrition, Nutrigenomic & Pharmacogenomics Nutrition,Anti Aging Nutrition, Infertility & Sex Nutrition) Skin Nutrition for Esthetic (Hair & Skin Nutrition, Cosmeceuticals/Cosmetic Nutrition, Body Shaping Nutrition, Fat & Cellulite Nutrition, etc)
Obesity and the risk of Infertility
Introduction : Many people don’t understand that obesity has the link factor for getting infertility. So, this abstract wants to discuss how obesity can increase a person’s risk of suffering infertility. Methode : Review study Results : Obesity and overweight people have high risk for reproductive disorder. Obesity is excessive fat accumulation condition. Human adipose tissue produces a variety of secretory factors. The secretory factors of adipose tissue release are free fatty acid,high leptin levels in serum and follicular fluid, hormone, cytokine or chemokines such as TNF alpha, IL-6, IL-8, leptin and adiponectin etc. So, adipose tissue in obese men and women is in pro inflammatory condition. Leptin is a stimulatory effect on the HPG axis to initiate the reproductive maturation of the hypothalamus. Leptin levels are higher in people who are obese. Discussion : Obesity is linked to infertility in both genders. Infertility in obese people has relationship with pro inflammatory condition. Obesity in men affect fertility by impaired spermatogenesis, erectile dysfunction, reduced the hormone testosterone levels, poor libido which has relationship with the HPG and hypothalamic pituitary adrenal axes. Leptin is a hormone that plays a role in many metabolic functions, including reproduction. High concentration of leptin has relationship to azospermia, oligozoospermia and oligo astheno teratozoospermia in obese men. Conclusion :Obesity has relationship to infertility cause of obesity has adipose tissue accumulation which produces many secretory factors. So, obesity in the pro-inflammatory condition will disturb normal reproductive function.
Key words : Obesity, Adipose Tissue, Infertility, Secretory Factors