International Conference on Cancer Science, Diagnosis and Therapeutics

Dhananjay Vithalrao Mane

Biography

1. NAME : Dr. Dhananjay Vithalrao Mane (Professor & Head of Dept. of Chemistry) Dr. Babasaheb Ambedkar Marathwada University?s Shri Chhatrapati Shivaji College, Omerga (MS) * Date of Birth & Age : 28/08/1967 & Age : 54 Years. 2. QUALIFICATION : 1990- M. Sc. (Chem.)., 1991- B.Ed., 1996 - Ph.D., 2012- MBA 3. PRESENT DESIGNATION : Director & Professor (since Feb. 2018) 4. ADDRESS : Yashwantrao Chavan Maharashtra Open University, Nashik ?422 002 (MS), India 5. Office Phone/Mobile : Office: 0253 2315773, Mobile : 94237 40832, 7972872532 Email : dvmane11@gmail.com ; rd_nashik@ycmou.digitaluniversity.ac 6. FELLOWSHIP/AWARD : 1. UGC- Teacher Research Fellows Award (1994-95) 2. Best NSS Programme Coordinator Award by Govt. of Maharashtra(MS) India (2008) 3. Best NSS Programme Officer Award by Dr. BAM University , Aurangabad (MS) India (2006) 7. TEACHING EXPERIENCE : 32 Years Teaching Experience Over Three decades (31years) & (Administrative Experience : 12 years as Professor : 12 years (2009-2022) as Reader/Associate Professor :10 years (1999-2009) and as Sr. Lecturer : 9 years (1990-1999).) 9. RESEARCH EXPEREINCE : 30 Years : Chemistry & Pharmacy. : 14 Students Awarded Ph. D. : 10 Students Working for Ph. D. 10. AREA OF RESEARCH : Drug Design, Forensic Science, Synthetic Organic Chemistry, Pharmaceutical Chemistry., Medicinal Chemistry, Analytical Chemistry, Nanomaterials, Pharmaco-Kinetic chemistry 11. Patents : 02 01 . Triamino triazine derivatives as a Potent reverse transcriptase inhibition of HIV-1. No.PCT/IN/ 2015/000386; International Patent; WIPO/PCT dated 21/04/2016 (Granted) 02 . Triamino triazine derivatives as a Potent reverse transcriptase inhibitor of HIV-1 Indian Patent/3238/MUM/2014 Indian Patent Office Journal(14658) dated 15/04/2016 (Granted) 12 Reviewer of Journals : 08 International Journals Editorial Board Member : 06 International Journals 13. Reviewer of Journals : 06 International, 06 National Journals 14. RESEARCH ACTIVITIES / PAPERS : i. Paper published in journals : 106 at National & International Level. ii. Papers presented in conferences : 65 at National Level : 30 at International Level iii. Chairman : Technical Session at National & International conf., iv. Referee : Evaluator of Ph. D Thesis of 04 Universities in India. v. Reviewer of Journals : 06 International Journals, 05 National Journals. 15. RESEARCH PROJECTS : 05 Minor Research Project Completed. : 01 UGC- Major Research Project Completed. 16. BOOK WRITING/ EDITED : 19, 08 Books Edited , 14 Books written. 17. Conferences /Seminars Organized : 10 National 04 International 06 State Level 18. WORKED ON UNIVERSITY BODIES / COMMITTEES : a. Chairman of Standing committee (2011-2015), Dr. Babasaheb Ambedkar Marathwada University, Aurangabad (MS) India b. Member of Standing committee (2011-2016), Dr. Babasaheb Ambedkar Marathwada University, Aurangabad. (MS) India c. Member of Senate (2011- 2016), Dr. Babasaheb Ambedkar Marathwada University, Aurangabad. (MS) India d. Member of Advisory committee, Dr. BAM Univ. Sub campus, Osmanabad (MS) India e. Member of Advisory committee, Dr. BAM University, NSS Cell.(2011-2017) f. Member of Advisory committee, Dr. BAM University, NSS Cell.(2011-2017) g. Chairman & Member of Vigilance Squad , Dr. BAM University, Exams., h. Chairman & Member of Affiliation Committee , Dr. BAM University, Aurangabad i. Subject Expert, Nominated by Vice Chancellor on Selection committee j. Member of Selection committee of Professors, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad. k. Member of Selection committee of Professors, Mumbai University, Mumbai. l. Member of Selection committee of Professors, Shivaji University, Kolhapur. m. Member of Examiner/ Paper setter panel : 1. SRT University, Nanded (MS) ; 2. Dr. BAM University, Aurangabad (MS) 3. Yashwantrao Chavan Maharashtra Open University, Nashik (MS) 4. Gulbarga University, Gulbarga 19. POSITIONS HELD ; 1 . NSS Programme Coordinator, Dr. BAM University. Aurangabad (2006-2010) 2. Dy. Director, UGC-HRDC, (Academic Staff College) Dr. Babasaheb Ambedkar Marathwada University, Aurangabad. (2013-2017) 20. LIFE MEMBER OF VARIOUS BODIES : 1. Life Member of Indian Science Congress, Kolkatta, INDIA 2. Life Member of Indian Chemical Society, Kolkatta, INDIA 3. Life Member of International Society of Chemists and Biologists, CDRI, Lucknow. 4. Life Member of Association of Chemistry Teachers, Mumbai, INDIA 5. Life Member of Chemical Research Society of India, IISc, Bangalore, INDIA 6. Life Member of International Congress of Chemistry & Environment, Indore 7. Life Member of Vigyan Prasar, DSIR, GOI, New Delhi. INDIA 8. Life Member of Indian Council of Chemist, Agra , INDIA 9. Fellow Member of International Congress of Chemistry & Environment, Indore. 21. VISITS TO ABROAD : (2009) -Thailand, (2010) - Malaysia, Singapore, (2012)- Srilanka, (2013)- Belgium, France, Germany,(2014) Italy, Netherland, Switzerland, Mauritius (2015) (Prof. Dr. Dhananjay Vithalrao Mane )

Research Interest

Abstract

Cancer chemotherapy has been one of the major medical advances in the last few decades. The medications involved in treatment have a narrow therapeutic index, and often the responses produced are only just palliative as well as unpredictable. In contrast, targeted therapy such as Tyrosine kinases inhibitors, that has been introduced in recent years is directed against cancer-specific molecules and signaling pathways with some side effects Therefore, we studied these class of molecules to obtain new candidates of remarkable activities and minimal side effects. We herein reported SAR driven synthesis of 16 novel molecules and their anticancer profiles in specifically targeted human Breast cell line MCF-7 and Human Colon Cancer Cell Line HCT-15. Compounds 7e and 8f showed descent antitumor activities when compared to Doxorubicine (GI50?